Bupivacaine, Ketamine And Bupivacaine – Ketamine Epidural Anaesthesia In Bitches Undergoing Ovariohysterectomy

This research was conducted to analyze the analgesic effects of bupivacaine, ketamine and bupivacaine–ketamine combination on bitches undergoing ovariohysterectomy, determine a suitable regional anaesthesia. Fifteen (15) apparently healthy bitches, aged 8-12 months weighing 10 – 15kg were procured within around Zaria, Kaduna State for this experiment. The animals grouped into three (3), A, B C, screened allowed acclimatize new environment. Premedication instituted with 0.02 mg/kg atropine sulphate 1mg/kg Xylazine. Group A administered an epidural injection 0.5 % bupivacaine hydrochloride at 1 mg/kg, 50 mg/ml 2 C 0.5mg/kg respectively. Analgesic indices determined time sphincter relaxation, onset action, duration analgesia muscle relaxation. standard ovariohysterectomy procedure carried out each experimental animal, lasting average 45 minutes. Bitches in group took longer (73 ± 18.0 secs) relaxation which significantly different from other groups. Ketamine shortest amount (15 3.0 almost immediate. (3 1.0 mins) only. produced (121 7.0 significant (110 20.0 mins). superior than those or alone used injection, sufficient painful surgeries such as dogs.